Omega 3 and Inflammatory Bowel Disease: How to Improve Symptoms of IBD, Crohn's Disease and Ulcerative Colitis Naturally
OMEGA 3 and INFLAMMATORY BOWEL DISEASE:
Inflammatory bowel disease (IBD) is serious inflammation in the digestive organs caused by autoimmune, a condition when the immune system attack the healthy tissues along digestive system organs. Crohn’s disease and Ulcerative colitis are two types of inflammatory bowel disease.
Omega-3 fatty acids are well-known as effective anti-inflammatory properties. They can be found in cold-water fish such as salmon, halibut, sardines, trout, or herring. Precursors to the most active omega-3s (eicosapentaenoic acid [EPA] and docosahexaenoic acid [DHA]) can be obtained in walnut oil, flaxseed oil, perilla oil, and canola oil. Omega-3 fatty acids have been shown to reduce inflammation in inflammatory bowel disease by reducing the production of inflammatory cytokines. They may also reduce the dosage of corticosteroid drugs needed to cause a remission.
Studies have shown that a combination of Omega-3 fatty acids and antioxidant, including vitamin A, vitamin C, vitamin E, and selenium, can reduce the symptoms associated with IBD.
The best natural source of Omega-3s comes from the oil the greenlip mussel (GLM) of New Zealand. It is at least 200 times more effective than fish oil at reducing inflammation in controlled laboratory experiments containing the normal polyunsaturated fatty acids (PUFAs). This is due to a series of unique Omega-3 PUFA's called eicosatertraenoic acids (ETA). Another bigger difference between fish oil and GLM is that fish oil will thin the blood and also affect blood clotting, whereas GLM will thin the blood but will not affect blood clotting.
Another interesting studies had been showed that Lyprinol (stabilised lipid extract of New Zealand green lipped mussel) is a potential preventative treatment modality for IBD.
Lyprinol, the stabilised lipid extract of the New Zealand green-lipped mussel, is currently used to relieve symptoms of arthritis. We investigated the effect of pretreatment with lipid extract of the New Zealand green lipped mussel on experimentally induced IBD in mice.
METHODS: Male C57BL/6 mice (aged 6 weeks) were gavaged daily for 13 days with (150 microl) olive oil (n = 7), fish oil (n = 8), or Lyprinol (n = 8). Mice consumed 2% dextran sulfate sodium (DSS) for 6 days, starting on day 7. Body weight and disease activity index (DAI) scores were recorded daily. Colonic damage was determined by histopathology. Colonic inflammation was quantified by myeloperoxidase (MPO) activity.
RESULTS: lipid extract of the New Zealand green-lipped mussel treatment significantly reduced body weight loss, DAI scores, crypt area losses, and cecum and colon weights, compared with FO treatment. MPO activity was not significantly affected by any treatment.
CONCLUSIONS: These findings provide preliminary evidence that lipid extract of the New Zealand Mussels may be potentially useful in ameliorating symptoms of IBD. The benefit, however, is unlikely to be due to the omega-3 fatty acid content. Dose-response evaluation of lipid extract of the New Zealand green-lipped mussel in experimental IBD is warranted.
The connection between Omega 3 and inflammatory bowel disease is an useful education for any patients who experienced IBD, Crohn's disease and Ulcerative colitis.
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Disclaimer: The material on this site is for informational and educational purposes only, and is not a substitute for medical advice, symptoms, diagnosis, or treatment provided by a qualified health care provider. You should consult with your own doctor regarding any relevant health issues you have.
